Sleep onset via thermoregulation
Glycine supports peripheral vasodilation and heat dissipation, helping the body create the core-temperature drop that naturally precedes sleep onset.
Supplements
Precision Glycine
The dedicated sleep companion that supports the temperature drop your body uses to fall asleep.
Falling asleep is not just about feeling tired. One of the body’s key sleep-onset signals is a drop in core body temperature. When that shift happens smoothly, the transition into sleep usually does too.
Who it's for
For adults who want support with sleep onset, more settled nights, and clearer mornings without relying on a heavy or habit-forming nighttime routine.
The Temperature Drop That Starts Better Sleep
3g/day | 30–60 minutes before bed | Paired with: Precision Sleep™ (Stack 12)
Why This Matters
Here’s a sleep fact that changes how most people think about falling asleep: your body doesn’t fall asleep because it’s tired. It falls asleep because your core body temperature drops. That’s the physiological trigger.
When your core temperature decreases by even 1–2 degrees, it signals to your brain that it’s time to initiate sleep. This is why you sleep better in a cool room, why a hot bath before bed paradoxically helps (it causes a rebound temperature drop), and why you toss and turn on hot nights.
Glycine taps directly into this mechanism. It induces peripheral vasodilation — meaning it opens up the blood vessels in your hands and feet, allowing heat to radiate outward from your extremities. The result? Your core temperature drops naturally, and your body enters sleep onset more easily.
But that’s not all it does. In a randomised controlled trial using glycine-rich collagen peptides, participants experienced significantly fewer nighttime awakenings (confirmed by polysomnography — the gold standard of sleep measurement) and improved next-morning cognitive performance. So it’s not just about falling asleep — it’s about staying asleep and waking up sharper.
Precision Glycine™ is the powder companion for Precision Sleep™. While the capsule stack handles melatonin support, brain-calming magnesium L-threonate, and GABA pathway modulation, the glycine adds the thermoregulatory mechanism that completes the picture. It’s exceptionally well-tolerated, has no known adverse effects at this dose, and is non-habit-forming.
Product Details
Detail Specification Active Ingredient Glycine (pharmaceutical grade amino acid) Source CanPrev or AOR — Canadian-sourced Daily Dose 3g (one level scoop) Timing 30–60 minutes before bed Format Unflavoured powder with a naturally mild sweetness Primary Pairing Precision Sleep™ (Stack 12)
The Evidence — Why We Chose This
Every product in the Precision line is here for a reason. Here’s the science behind this one.
Sleep Onset via Thermoregulation
Glycine induces peripheral vasodilation, facilitating heat dissipation from the extremities and reducing core body temperature — the primary physiological trigger for sleep onset. This is the same mechanism your body uses naturally; glycine supports the process when it’s sluggish.
Sleep Quality (Polysomnography)
RCT using glycine-rich collagen peptides: significantly reduced nighttime awakenings, confirmed by polysomnography (gold standard sleep measurement). Participants also reported improved subjective sleep quality and reduced next-day fatigue.
Next-Morning Cognitive Performance
The same RCT demonstrated improved cognitive performance the following morning — suggesting that glycine doesn’t just improve sleep duration, but sleep quality in a way that translates to daytime function.
Safety and Tolerability
Glycine is one of the simplest amino acids and is exceptionally well-tolerated. No known adverse effects at 3g/day. Non-sedating in the traditional sense — it works through thermoregulation, not central nervous system depression, which means no grogginess.
Important Considerations
This product is well-researched and appropriate for most healthy adults. The following points are worth knowing — particularly if you are taking prescription medications or have specific health conditions. When in doubt, share this information with your prescribing physician.
Drug Interactions
Glycine has no significant known drug interactions at this dose. It’s one of the cleanest sleep-support compounds available. If you are taking clozapine or other antipsychotic medications, discuss with your prescribing physician as glycine may have additive effects on NMDA receptor modulation.
These statements have not been evaluated by Health Canada or the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. The evidence summaries provided are for educational purposes and represent published research findings. If you are pregnant, nursing, taking medication, or have a health condition, please consult your healthcare provider before use.
Complete Your Protocol
Precision Glycine™ is the dedicated powder companion for Precision Sleep™. For a complete sleep protocol, pair with Precision Sleep™ + Precision Fibre™ + Precision Creatine™.
Not sure where to start? Book a complimentary 15-minute coaching call.
What's Inside
Every ingredient. Every dose. On the label.
| Ingredient / Detail | Dose / Value | Timing | Why It Matters |
|---|---|---|---|
Active ingredient Glycine (pharmaceutical grade amino acid) | Glycine (pharmaceutical grade amino acid) | Reference | Core product detail for format, dose, sourcing, or pairing. |
Source CanPrev or AOR - Canadian-sourced | CanPrev or AOR - Canadian-sourced | Reference | Core product detail for format, dose, sourcing, or pairing. |
Daily dose 3g (one level scoop) | 3g (one level scoop) | Reference | Core product detail for format, dose, sourcing, or pairing. |
Timing 30-60 minutes before bed | 30-60 minutes before bed | Reference | Core product detail for format, dose, sourcing, or pairing. |
Format Unflavoured powder with a naturally mild sweetness | Unflavoured powder with a naturally mild sweetness | Reference | Core product detail for format, dose, sourcing, or pairing. |
Primary pairing Precision Sleep™ | Precision Sleep™ | Reference | Core product detail for format, dose, sourcing, or pairing. |
Glycine Sleep-support amino acid Timing: Before bed Supports sleep onset through thermoregulation and may help reduce nighttime disruption without a heavy sedative feel. | 3g | Before bed | Supports sleep onset through thermoregulation and may help reduce nighttime disruption without a heavy sedative feel. |
The Story
Why this formula was built this way.
Glycine supports this by encouraging peripheral vasodilation, helping heat move out through the extremities so core temperature can fall more naturally. That makes it a useful match for people who feel wired at night, run warm, or have trouble settling into sleep.
Precision Glycine pairs with Precision Sleep to round out the protocol. The stack handles melatonin support and calming neurochemistry, while glycine adds a thermoregulation-based mechanism that helps complete the sleep picture.
The Evidence
Why this formula made the cut.
Educational summary. Not a substitute for personalised medical advice.
Sleep quality
Randomised controlled data using glycine-rich collagen peptides has shown fewer nighttime awakenings and improved subjective sleep quality, with polysomnography support in trial settings.
Next-morning function
The same research also suggests better next-day cognitive performance and less fatigue, making glycine relevant not only for bedtime but for how you function the next morning.
Tolerance profile
At the doses commonly used for sleep support, glycine is generally very well tolerated and works through thermoregulation rather than a strong sedative effect, which helps avoid a heavy hangover feeling.
Important Considerations
A few things to know before you start.
Medication interactions
1Glycine has few notable interactions at this dose, but if you take clozapine or other medications affecting NMDA signalling, share it with your prescribing clinician before use.
Important. These statements have not been evaluated by Health Canada or the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. The evidence summaries provided are for educational purposes only and represent published research findings - they are not claims about this specific product's ability to treat any condition. If you are pregnant, nursing, taking medication, or have a health condition, please consult your healthcare provider before use.