Cellular energy, mitophagy, and healthy aging support in one foundational daily protocol.
Here's a number that stops most people: NAD+ levels drop roughly 50% between ages 40 and 60. NAD+ is the molecule your cells need to produce energy, repair DNA, and activate the longevity pathways that keep you functioning at your best.
For anyone looking to optimise the foundational mechanisms of cellular aging. Ideal if you're experiencing fatigue, want to support longevity pathways, or are seeking a comprehensive micronutrient base.
| Ingredient / Detail | Dose / Value | Timing | Why It Matters |
|---|---|---|---|
NMN 600mg (AOR NMN-600) NAD+ precursor Timing: AM Supports cellular energy, DNA repair, and sirtuin activation. | 1 cap | AM | Supports cellular energy, DNA repair, and sirtuin activation. |
Urolithin A (AOR Urolithin A+) Mitophagy activator Timing: AM Clears damaged mitochondria and supports muscle endurance. | 1 cap | AM | Clears damaged mitochondria and supports muscle endurance. |
Multi Basics 3 (AOR) Activated multinutrient base Timing: AM + PM Provides activated B vitamins and foundational micronutrient coverage. | 2 caps | AM + PM | Provides activated B vitamins and foundational micronutrient coverage. |
Omega-3 EPA/DHA (DFH OmegaAvail Hi-Po) High-potency fish oil Timing: AM Supports cardiovascular health, brain function, and cell membrane integrity. | 2 caps | AM | Supports cardiovascular health, brain function, and cell membrane integrity. |
Quercetin 500mg (AOR) Polyphenol senolytic support Timing: PM Supports senolytic activity, antioxidant defence, and blood pressure balance. | 1 cap | PM | Supports senolytic activity, antioxidant defence, and blood pressure balance. |
D3 1000IU + K2 (CanPrev) Vitamin D + K complex Timing: PM Supports bone density, vascular calcium routing, and immune modulation. | 2 caps | PM | Supports bone density, vascular calcium routing, and immune modulation. |
Magnesium Bisglycinate 200mg (CanPrev) Chelated magnesium Timing: PM Supports sleep, cardiovascular health, glucose regulation, and over 300 enzymatic reactions. | 1 cap | PM | Supports sleep, cardiovascular health, glucose regulation, and over 300 enzymatic reactions. |
When NAD+ falls, everything downstream starts to slow. Energy production slows. Cellular cleanup slows. Your body's ability to clear out old, damaged cells slows too. Think of it like a maintenance crew in a large building. When the crew is fully staffed, everything runs smoothly. Cut that crew in half, and things start to pile up.
Precision Longevity Core is designed around the foundational mechanisms of cellular aging: NAD+ replenishment, mitochondrial quality control, senolytic support, and the broad-spectrum micronutrient base your body needs to run hundreds of enzymatic reactions every day. This is the stack we'd suggest most people start with, because these are the pathways everything else depends on.
Educational summary. Not a substitute for personalised medical advice.
Human trial data confirms meaningful NAD+ elevation and improved physical performance metrics at 600mg daily. NAD+ sits at the center of cellular energy production, DNA repair, and metabolic signalling, so restoring it has system-wide implications.
Published human data shows Urolithin A improves muscle endurance and mitochondrial gene expression versus placebo. It works by activating mitophagy, the quality-control pathway that helps your cells retire damaged mitochondria and replace them with healthier ones.
Quercetin has senolytic relevance across multiple studies and meta-analytic support for modest blood pressure improvement plus reductions in inflammatory markers such as TNF-alpha and IL-6. It helps support clearance of dysfunctional, pro-inflammatory cells.
A large evidence base shows omega-3s reduce triglycerides, blood pressure, heart rate, and inflammatory tone. It remains one of the most consistently supported supplements in the literature for cardiovascular and membrane health.
D3 and K2 work as a pair. D3 supports calcium absorption and immune signalling, while K2 helps direct that calcium into bone rather than soft tissue. This is especially relevant when longevity support also means preserving bone and vascular health over time.
Magnesium participates in hundreds of enzymatic reactions tied to glucose regulation, cardiovascular tone, sleep quality, and stress resilience. The bisglycinate form is well tolerated and avoids the GI irritation associated with lower-quality forms.
If you are taking blood-thinning medications such as warfarin, aspirin, or clopidogrel, review the omega-3 portion of this stack with your prescribing physician before starting.
Quercetin may interact with certain antibiotics, cyclosporin, and blood-thinning medications. If you use prescription medications, review this stack with your healthcare provider first.
NMN is generally well tolerated, but if you have a personal or family history of hormone-sensitive conditions, share this formula with your healthcare provider before starting.
Vitamin D3 is fat-soluble and accumulates over time. If you are using more than one Precision stack that contains D3, confirm with your healthcare provider that your combined daily total remains appropriate for you.
Important. These statements have not been evaluated by Health Canada or the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. The evidence summaries provided are for educational purposes only and represent published research findings - they are not claims about this specific product's ability to treat any condition. If you are pregnant, nursing, taking medication, or have a health condition, please consult your healthcare provider before use.
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