Citicoline 250mg
Multiple human trials show citicoline improves attention, memory, and processing speed. It supplies both the choline needed for acetylcholine and the building blocks used to repair neuronal membranes.
Clarity, memory, and neuroprotection built around brain energy, membranes, and neurotransmitter support.
Your brain uses roughly 20% of your total energy output. It's the most metabolically demanding organ in your body, and one of the most sensitive to mitochondrial decline.
For anyone experiencing brain fog, concentration difficulties, or memory changes. Ideal if you work in cognitively demanding roles, want to optimise mental clarity, or are concerned about cognitive aging.
Clarity, Memory, and Neuroprotection
Who is this for?
For anyone experiencing brain fog, concentration difficulties, or memory changes. Ideal if you work in cognitively demanding roles, want to optimise mental clarity, or are concerned about cognitive ageing.
Your brain uses roughly 20% of your total energy output. It’s the most metabolically demanding organ in your body. And the one most sensitive to mitochondrial decline. So when people tell us they’re experiencing brain fog, difficulty concentrating, or that unsettling feeling that their memory isn’t what it used to be, the first question we ask isn’t ‘what’s wrong with your brain?’ It’s ‘what’s happening with your brain’s energy supply?’ Here’s the thing: DHA, the omega-3 fatty acid, makes up approximately 40% of the fatty acids in your brain. Phosphatidylserine keeps your neuronal membranes fluid and functional. Citicoline is the raw material for acetylcholine, the neurotransmitter that drives memory and processing speed. And Magnesium L-Threonate? It’s the only form of magnesium shown to actually cross the blood-brain barrier in clinically meaningful amounts. Precision Mind brings all of these together in a single daily compliance pack, targeting the three pillars of cognitive performance: neuronal energy production, membrane integrity, and neurotransmitter support.
Daily dose: 8 caps/day | Timing: AM + PM
Ingredient Dose Timing Role in This Formula Citicoline 250mg (AOR) 2 caps AM + PM Acetylcholine precursor and phosphatidylcholine synthesis. Supports memory and processing speed. COGNI-Q: PQQ 20mg + CoQ10 300mg (AOR) 1 cap AM Mitochondrial neurogenesis (PQQ) and cellular energy production (CoQ10) for brain function. PS-100 Phosphatidylserine 100mg (AOR) 1 cap PM Neuronal membrane integrity, cortisol regulation, memory consolidation. Magnesium L-Threonate (CanPrev) 1-2 caps PM Brain-bioavailable magnesium. Supports synaptic plasticity, deep and REM sleep. R-Lipoic Acid (AOR) 1 cap AM Mitochondrial antioxidant, glucose metabolism, nerve protection. Ultra DHA Omega-3 (DFH OmegaAvail) 2 caps AM DHA-dominant formula. Structural brain fatty acid and neuroplasticity support.
Companion Powders: Precision Creatine (5g/day) + Precision Fibre (5-10g/day)
Why each ingredient is here.
Multiple RCTs confirm citicoline supplementation improves attention, memory, and processing speed in adults. So what does citicoline actually do? It provides the choline your brain needs to build acetylcholine, that’s the neurotransmitter responsible for focus and recall. And the CDP-choline for repairing neuronal membranes. Think of it as both fuel and building material for the brain’s communication network. Citation: Cotroneo, A.M., et al. (2013). Effectiveness and tolerability of cytidine diphosphate choline in patients affected by cognitive decline. Clinical Interventions in Aging. 8.
PQQ does something remarkable: it stimulates nerve growth factor and mitochondrial biogenesis. Literally growing new mitochondria in brain cells. CoQ10 is the electron carrier powering mitochondrial ATP production. Together, they address both energy production and mitochondrial renewal simultaneously. It’s the difference between just running the factory and actually upgrading the equipment. Citation: Akagawa, M., et al. (2016). An evaluation of pair-wise interaction between pyrroloquinoline quinone and alpha-tocopherol using immortalised HepG2 cells. Journal of Clinical Biochemistry and Nutrition. 58(1).
Cochrane review and multiple RCTs confirm phosphatidylserine improves memory, learning, and concentration, particularly in age-related cognitive changes. It’s a key component of neuronal cell membranes. Keeping those membranes fluid and responsive is how your brain cells communicate efficiently. Citation: Jorissen, B.L., et al. (2001). Phosphatidylserine supplementation in elderly people. Effects on memory complaints and state anxiety. Human Psychopharmacology. 16(7).
This is the form that matters for the brain. Standard magnesium doesn’t cross the blood-brain barrier in meaningful amounts. L-Threonate does. RCT using wearable tracking: significantly improved deep sleep score, REM sleep, HRV, and cognitive readiness vs placebo. Better brain magnesium means better synaptic plasticity. Which is how your brain forms and retrieves memories. Citation: Slutsky, I., et al. (2010). Enhancement of learning and memory by elevating brain magnesium. Neuron. 65(2).
Meta-analysis confirms significant reduction in fasting blood sugar, HbA1c, TNF-alpha, IL-6, and CRP. What makes R-Lipoic Acid unique among antioxidants is that it’s both water- and fat-soluble. Meaning it can protect every compartment of every cell. The R-form is the naturally occurring, more bioactive version. Citation: Goraca, A., et al. (2011). Alpha-lipoic acid in cardiac ischemia/reperfusion injury. Postepy Higieny i Medycyny Doswiadczalnej. 65.
DHA constitutes approximately 40% of the fatty acids in the brain. That’s not a minor detail. It’s the structural foundation. Systematic reviews confirm DHA supplementation supports cognitive performance, reduces neuroinflammation, and is associated with lower risk of cognitive decline in prospective studies. Citation: Yurko-Mauro, K., et al. (2010). Beneficial effects of docosahexaenoic acid on cognition in age-related cognitive decline. Alzheimer’s and Dementia. 6(6).
CoQ10 and Blood Pressure: CoQ10 at higher doses may have mild blood-pressure-supporting effects. If you are on antihypertensive medications, monitor your blood pressure when starting this formula. It may also interact with anticoagulants such as warfarin. Please share this information with your prescribing physician.
R-Lipoic Acid Timing: Best absorbed on an empty stomach. If you are on thyroid medication, please space this supplement at least 2 hours apart. Also has trace chelating properties. Take 2 hours away from iron or mineral supplements.
Omega-3 and Blood-Thinning Medications: If you are taking blood-thinning medications, please share this with your prescribing physician before starting this formula.
Health Canada/FDA: These statements have not been evaluated by Health Canada or the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
Educational Purpose: The evidence summaries provided are for educational purposes and represent published research findings. Individual results may vary. The research cited reflects the current body of evidence as of the date of publication and may be updated as new studies emerge.
Medical Consultation: This product is a wellness supplement, not a prescription medication. It is not a substitute for medical advice, diagnosis, or treatment. Always consult your healthcare provider before starting any new supplement, especially if you are pregnant, nursing, taking medication, or have a pre-existing health condition.
Drug Interactions: Some ingredients in this formula may interact with prescription medications. Please review the Important Considerations section and share this information with your prescribing physician.
Dev Note (CPSO Compliance): All content on this page is educational and wellness-focused. No diagnostic or prescriptive claims are made. Content complies with CPSO advertising guidelines.
Citicoline and phosphatidylserine effects on attention and memory typically emerge within 2-4 weeks. Many people report improved mental clarity within 1-2 weeks. DHA and Magnesium L-Threonate support deeper changes in neuronal membrane integrity and sleep quality, typically showing measurable effects within 4-8 weeks.
Yes. In fact, this stack is designed to complement your existing routines. The neurotransmitter and mitochondrial support actually enhances your brain’s ability to use caffeine efficiently. Just avoid taking R-Lipoic Acid immediately before caffeine, as both can increase alertness. Separate by 1-2 hours for optimal absorption.
Yes. Many people experience brain fog during hormonal transitions (perimenopause, andropause, cortisol dysregulation). This stack targets the mitochondrial and membrane-level causes of that fog. Magnesium L-Threonate specifically helps with stress-related cognitive changes. If your brain fog is hormone-driven, consider pairing this with Precision Female or Precision Male.
For cognitive function specifically, yes. DHA is the structural component of brain tissue. EPA is more cardiovascular-focused. This stack uses a DHA-dominant formula because the brain has higher affinity for DHA. If you’re also concerned about cardiovascular health, Precision Longevity Core (which has balanced EPA+DHA) makes an excellent companion stack.
Cotroneo, A.M., et al. (2013). Effectiveness and tolerability of cytidine diphosphate choline in patients affected by cognitive decline. Clinical Interventions in Aging. 8.
Akagawa, M., et al. (2016). An evaluation of pair-wise interaction between pyrroloquinoline quinone and alpha-tocopherol using immortalised HepG2 cells. Journal of Clinical Biochemistry and Nutrition. 58(1).
Jorissen, B.L., et al. (2001). Phosphatidylserine supplementation in elderly people. Effects on memory complaints and state anxiety. Human Psychopharmacology. 16(7).
Slutsky, I., et al. (2010). Enhancement of learning and memory by elevating brain magnesium. Neuron. 65(2).
Goraca, A., et al. (2011). Alpha-lipoic acid in cardiac ischemia/reperfusion injury. Postepy Higieny i Medycyny Doswiadczalnej. 65.
Yurko-Mauro, K., et al. (2010). Beneficial effects of docosahexaenoic acid on cognition in age-related cognitive decline. Alzheimer’s and Dementia. 6(6).
This represents one stack in the Precision Longevity supplement collection. For a comprehensive consultation on which stacks are right for you, visit precisionlongevity.life or schedule a consultation.
| Ingredient / Detail | Dose / Value | Timing | Why It Matters |
|---|---|---|---|
Citicoline 250mg (AOR) Acetylcholine precursor Timing: AM + PM Supports acetylcholine production, phosphatidylcholine synthesis, memory, and processing speed. | 2 caps | AM + PM | Supports acetylcholine production, phosphatidylcholine synthesis, memory, and processing speed. |
COGNI-Q: PQQ 20mg + CoQ10 300mg (AOR) Mitochondrial brain-energy complex Timing: AM Supports mitochondrial renewal and cellular energy production for brain function. | 1 cap | AM | Supports mitochondrial renewal and cellular energy production for brain function. |
PS-100 Phosphatidylserine 100mg (AOR) Neuronal membrane lipid Timing: PM Supports membrane integrity, cortisol regulation, and memory consolidation. | 1 cap | PM | Supports membrane integrity, cortisol regulation, and memory consolidation. |
Magnesium L-Threonate (CanPrev) Brain-bioavailable magnesium Timing: PM Supports synaptic plasticity, deep sleep, and REM sleep quality. | 1-2 caps | PM | Supports synaptic plasticity, deep sleep, and REM sleep quality. |
R-Lipoic Acid (AOR) Universal antioxidant Timing: AM Supports mitochondrial antioxidant defence, glucose metabolism, and nerve protection. | 1 cap | AM | Supports mitochondrial antioxidant defence, glucose metabolism, and nerve protection. |
Ultra DHA Omega-3 (DFH OmegaAvail) DHA-dominant fish oil Timing: AM Provides structural brain fatty acids and supports neuroplasticity. | 2 caps | AM | Provides structural brain fatty acids and supports neuroplasticity. |
So when people tell us they're dealing with brain fog, concentration difficulty, or that unsettling feeling that memory is not what it used to be, the first question is not 'what's wrong with your brain?' It's 'what's happening with your brain's energy supply?'
DHA makes up roughly 40% of the fatty acids in the brain. Phosphatidylserine keeps neuronal membranes fluid. Citicoline supplies the raw material for acetylcholine, the neurotransmitter tied to memory and processing speed. Magnesium L-threonate is the form of magnesium best studied for meaningful brain delivery. Precision Mind brings those pillars together in one daily compliance pack.
Educational summary. Not a substitute for personalised medical advice.
Multiple human trials show citicoline improves attention, memory, and processing speed. It supplies both the choline needed for acetylcholine and the building blocks used to repair neuronal membranes.
PQQ supports mitochondrial biogenesis and nerve growth signalling, while CoQ10 helps drive ATP production. Together they address both brain energy output and mitochondrial renewal rather than only one side of the equation.
Clinical evidence supports phosphatidylserine for memory, learning, concentration, and stress resilience, especially where age-related cognitive changes are involved. It is a structural component of healthy neuronal membranes.
Unlike standard forms, magnesium L-threonate has been specifically studied for brain delivery. Trial data links it with better deep sleep, REM sleep, HRV, and cognitive readiness, all of which affect daily clarity.
R-lipoic acid is both water- and fat-soluble, which helps it protect multiple cellular environments. Evidence also supports benefits for oxidative stress, inflammatory tone, and glucose handling that can influence cognitive energy.
DHA is a structural brain fat, not just a general wellness add-on. Human and observational data connect DHA support with cognitive performance, lower neuroinflammatory load, and healthier aging trajectories for the brain.
CoQ10 at this dose may have mild blood-pressure-supporting effects and may interact with anticoagulants such as warfarin. If you use either, share this formula with your prescribing physician.
R-lipoic acid is best absorbed on an empty stomach. If you take thyroid medication, space this supplement at least 2 hours away. It should also be spaced away from iron or mineral supplements.
If you are taking blood-thinning medications, review the omega-3 portion of this stack with your prescribing physician before starting.
Important. These statements have not been evaluated by Health Canada or the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. The evidence summaries provided are for educational purposes only and represent published research findings - they are not claims about this specific product's ability to treat any condition. If you are pregnant, nursing, taking medication, or have a health condition, please consult your healthcare provider before use.