Skin, hair, and nails - from the inside out.
Here's what most skincare approaches get wrong: they focus entirely on the outside. Serums, creams, treatments - all working on the surface. But your skin is built from the inside. The collagen matrix, the hydration, the elasticity, the UV protection - these are driven by what's happening at the cellular level.
This stack is designed for someone actively seeking to optimise their precision radiance. If this resonates with where you are right now, this is your starting point.
Skin, Hair, and Nails—From the Inside Out
Who Is This For?
This stack is designed for someone actively seeking to optimise their precision radiance. If this resonates with where you are right now, this is your starting point.
Here’s what most skincare approaches get wrong: they focus entirely on the outside. Serums, creams, treatments—all working on the surface. But your skin is built from the inside. The collagen matrix, the hydration, the elasticity, the UV protection—these are driven by what’s happening at the cellular level. Collagen production declines roughly 1–1.5% per year after age 25. By the time wrinkles become visible, the structural decline has been happening for years. And here’s the key insight: vitamin C isn’t optional when it comes to collagen synthesis. It’s required. Without adequate vitamin C, the hydroxylation steps that form the collagen triple helix literally can’t happen. That’s not a marketing claim—it’s biochemistry. Precision Radiance pairs bioactive collagen peptides with the required vitamin C cofactor, oral hyaluronic acid (yes, it works when taken orally—the RCT data is clear), astaxanthin for photoprotection, and biotin + silica for hair and nail integrity. The result is a comprehensive approach to looking good that starts where it actually matters—from the inside out.
This stack contains 5 active ingredients, optimised for daily consistency. Total daily commitment: 4 caps + powder, taken AM + PM. Pair with: Precision Creatine™ 5g/day | Precision Fibre™ 5–10g/day
Ingredient Dose Timing Role in This Formula Collagen Peptides 5g (low molecular weight) 5g powder AM with Vitamin C Skin hydration, elasticity, wrinkle depth, nail quality Astaxanthin 6mg (AOR or DFH) 1 cap AM with fat-containing meal Photoprotection, skin moisture, UV defence, anti-inflammatory Biotin + Silica (botanical extract) 1 cap AM Hair growth rate, hair fall reduction, nail texture, skin elasticity Vitamin C 500mg (AOR) 500mg AM with collagen Essential collagen synthesis cofactor—hydroxylation of proline and lysine Hyaluronic Acid oral (low MW) 120mg (AOR or DFH) 1 cap PM Skin hydration, brightness, smoothness, epidermal thickness
Below is a summary of the research supporting each component. We’ve included formal citations so you can dig deeper if you want to.
Meta-analysis of 26 RCTs (1,721 participants): hydrolysed collagen supplementation significantly improved skin hydration and elasticity. 12-week RCT (collagen + Vitamin C): 44.6% decrease in collagen fragmentation, hydration +13.8%, elasticity +22.7%, wrinkle depth -19.6%. 90 days is the standard effective window. Low molecular weight peptides (Gly-Pro, Pro-Hyp) are the bioactive fractions most efficiently absorbed and utilised for skin matrix remodelling.
Meta-analysis of 9 RCTs: oral astaxanthin significantly improved skin moisture and elasticity. 16-week RCT: astaxanthin significantly increased minimal erythema dose (UV protection threshold) and prevented UV-induced moisture loss. Think of it as internal sunscreen support. It quenches reactive oxygen species in skin tissue more efficiently than vitamin E or beta-carotene.
90-day RCT: biotin + silica botanical extract significantly reduced hair fall, increased hair growth rate, improved nail roughness, and increased skin elasticity. Biotin supports keratin infrastructure; silica supports collagen cross-linking and structural integrity.
Vitamin C is a required cofactor for prolyl and lysyl hydroxylase—the enzymes responsible for the hydroxylation steps in collagen synthesis. Without adequate vitamin C, collagen triple helix formation is impaired. Co-administration with collagen peptides is mechanistically essential, not optional.
Double-blind RCT (129 women): oral HA supplementation significantly promoted skin hydration at 2–8 weeks, skin tone improvement at 4–8 weeks, and increased epidermal thickness at 12 weeks. Low molecular weight HA is absorbed orally and distributes systemically, stimulating endogenous HA synthesis in dermal fibroblasts. This isn’t topical—it works from the inside.
Before starting any new supplement, please review these clinical considerations. If you’re on prescription medications, share this page with your healthcare provider.
Biotin at supplemental doses
Biotin supplementation can interfere with certain laboratory blood tests—specifically thyroid hormone tests and cardiac troponin tests. If you have blood work scheduled, inform your healthcare provider and the laboratory that you are taking biotin, and consider pausing for 48 hours before the blood draw. This is a technical interaction with the test chemistry, not a harmful effect.
Astaxanthin
Fat-soluble—always take with a meal that contains some fat for optimal absorption. Very well tolerated at 4–12mg/day.
Vitamin C
At the dose in this formula (500mg), well within the comfortable range for most people. If you have a history of oxalate-type kidney stones, share higher-dose vitamin C use with your healthcare provider.
These statements have not been evaluated by Health Canada or the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
The evidence summaries provided are for educational purposes and represent published research findings. Individual results may vary. The research cited reflects the current body of evidence as of the date of publication and may be updated as new studies emerge.
This product is a wellness supplement, not a prescription medication. It is not a substitute for medical advice, diagnosis, or treatment. Always consult your healthcare provider before starting any new supplement, especially if you are pregnant, nursing, taking medication, or have a pre-existing health condition.
Some ingredients in this formula may interact with prescription medications. Please review the Important Considerations section above and share this information with your prescribing physician.
CPSO Compliance Note (Internal): All content on this page is educational and wellness-focused. No diagnostic or prescriptive claims are made. Content complies with CPSO advertising guidelines for health professionals in Ontario.
Most people don’t need just one stack. Consider combining with:
Collagen-related changes typically become visible around 8-12 weeks, though some people notice skin smoothness and hydration within 4-6 weeks. Hair growth cycles are longer—meaningful hair fall reduction takes 3-4 months, because hair growth is on a longer timeline. Nails show change at about 12 weeks (the time it takes to grow a full nail from root to tip). Patience is the common theme here.
The research is real. The 12-week RCT showed wrinkle depth reduction of -19.6%, which is clinically meaningful. That said, this is a modest improvement, not a miracle. It’s not botox. It’s appropriate for someone looking to slow the clock, not stop it entirely. If you’re 45 and want to minimise further decline, this works. If you’re 65 and hoping to erase 20 years, manage expectations.
Collagen peptides, vitamin C, and hyaluronic acid are all generally safe in pregnancy. Biotin at supplemental doses should be discussed with your OB. Astaxanthin safety in pregnancy hasn’t been as extensively studied, so we’d recommend pausing it during pregnancy and restarting postpartum. Definitely discuss the full formula with your healthcare provider before starting if you’re pregnant.
Bone broth is a food, and yes, it contains collagen. But the amount is variable, the collagen form is different, and you’d need to consume a very large volume to match the peptide dose in this formula. Also, our formula includes vitamin C (which bone broth doesn’t provide) as the required cofactor for synthesis. Think of bone broth as a helpful dietary addition and this formula as a targeted supplement—they’re complementary, not competitive.
The following studies support the evidence presented above:
Asserin, J., et al. (2015). The effect of oral collagen peptides on skin moisture and the dermal collagen network. Nutrients.
Kishimoto, Y., et al. (2018). Astaxanthin shows promise for improving age-related skin characteristics. Nutrients.
Gehring, W. (2016). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology.
| Ingredient / Detail | Dose / Value | Timing | Why It Matters |
|---|---|---|---|
Collagen Peptides 5g (low molecular weight) Hydrolysed collagen Timing: AM with vitamin C Skin hydration, elasticity, wrinkle depth, nail quality | 5g powder | AM with vitamin C | Skin hydration, elasticity, wrinkle depth, nail quality |
Astaxanthin 6mg (AOR or DFH) Marine carotenoid Timing: AM with fat-containing meal Photoprotection, skin moisture, UV defence, anti-inflammatory | 1 cap | AM with fat-containing meal | Photoprotection, skin moisture, UV defence, anti-inflammatory |
Biotin + Silica (botanical extract) Hair & nail support Timing: AM Hair growth rate, hair fall reduction, nail texture, skin elasticity | 1 cap | AM | Hair growth rate, hair fall reduction, nail texture, skin elasticity |
Vitamin C 500mg (AOR) Ascorbic acid Timing: AM with collagen Essential collagen synthesis cofactor - hydroxylation of proline and lysine | 500mg | AM with collagen | Essential collagen synthesis cofactor - hydroxylation of proline and lysine |
Hyaluronic Acid oral (low MW) 120mg (AOR or DFH) Low molecular weight HA Timing: PM Skin hydration, brightness, smoothness, epidermal thickness | 1 cap | PM | Skin hydration, brightness, smoothness, epidermal thickness |
Collagen production declines roughly 1-1.5% per year after age 25. By the time wrinkles become visible, the structural decline has been happening for years. And here's the key insight: vitamin C isn't optional when it comes to collagen synthesis. It's required. Without adequate vitamin C, the hydroxylation steps that form the collagen triple helix literally can't happen. That's not a marketing claim - it's biochemistry.
Precision Radiance pairs bioactive collagen peptides with the required vitamin C cofactor, oral hyaluronic acid (yes, it works when taken orally - the RCT data is clear), astaxanthin for photoprotection, and biotin + silica for hair and nail integrity. The result is a comprehensive approach to looking good that starts where it actually matters - from the inside out.
Educational summary. Not a substitute for personalised medical advice.
Meta-analysis of 26 RCTs (1,721 participants): hydrolysed collagen supplementation significantly improved skin hydration and elasticity. Twelve-week RCT with collagen plus vitamin C showed a 44.6% decrease in collagen fragmentation, hydration up 13.8%, elasticity up 22.7%, and wrinkle depth down 19.6%. Ninety days is the standard effective window. Low molecular weight peptides are the bioactive fractions most efficiently absorbed and used for skin matrix remodelling.
Meta-analysis of 9 RCTs: oral astaxanthin significantly improved skin moisture and elasticity. Sixteen-week RCT: astaxanthin significantly increased minimal erythema dose and prevented UV-induced moisture loss. It supports internal photoprotection by quenching reactive oxygen species in skin tissue more efficiently than vitamin E or beta-carotene.
90-day RCT: biotin + silica botanical extract significantly reduced hair fall, increased hair growth rate, improved nail roughness, and increased skin elasticity. Biotin supports keratin infrastructure; silica supports collagen cross-linking and structural integrity.
Vitamin C is a required cofactor for prolyl and lysyl hydroxylase - the enzymes responsible for the hydroxylation steps in collagen synthesis. Without adequate vitamin C, collagen triple helix formation is impaired. Co-administration with collagen peptides is mechanistically essential, not optional.
Double-blind RCT (129 women): oral HA supplementation significantly promoted skin hydration at 2-8 weeks, skin tone improvement at 4-8 weeks, and increased epidermal thickness at 12 weeks. Low molecular weight HA is absorbed orally and distributes systemically, stimulating endogenous HA synthesis in dermal fibroblasts.
Biotin supplementation can interfere with certain laboratory blood tests - specifically thyroid hormone tests and cardiac troponin tests. If you have blood work scheduled, inform your healthcare provider and the laboratory that you are taking biotin, and consider pausing for 48 hours before the blood draw. This is a technical interaction with the test chemistry, not a harmful effect.
Astaxanthin is fat-soluble - always take with a meal that contains some fat for optimal absorption. Very well tolerated at 4-12mg per day.
At the 500mg vitamin C dose used here, most people tolerate it comfortably. If you have a history of oxalate-type kidney stones, share higher-dose vitamin C use with your healthcare provider.
Important. These statements have not been evaluated by Health Canada or the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. The evidence summaries provided are for educational purposes only and represent published research findings - they are not claims about this specific product's ability to treat any condition. If you are pregnant, nursing, taking medication, or have a health condition, please consult your healthcare provider before use.